While the adrenal glands still help out with testosterone and progesterone production in later years, the amount supplied is extremely small. The biggest issue that we see is an end to normal estrogen levels when the body converts excess testosterone into estradiol. This causes an imbalance that leads to a condition called estrogen dominance – where estrogen is now unopposed by progesterone and testosterone because their levels have declined. Estrogen dominance leads to weight gain, which further increases testosterone to estrogen conversion.
This is a common problem with pellets. If you go looking for forums on the matter, you will see that it is rather typical for patients to have a similar response somewhere around the 4th and 5th implantation. This stems from poor oversight/management, and design flaws in the pellets themselves. Keep in mind that all pellets are made the same way. This may seem beneficial at first glance, however, what this really means is that “6 months” worth of medication dissolves in a way that sends your levels far too high in the first month, and then plummeting far too fast and low in the next 2-3.
My brother has been compounding my hormones since 2000. I just saw a doctor who ordered blood tests to check my hormone levels, primarily because my hair won't stop falling out. The doctor's office faxed the results to my brother and she had prescribed testosterone cream on the labia. I didn't like that answer and now the doctor is in Australia until mid January. The way my brother explained it is that the testosterone will increase the libido, it will build up muscle tissue and do several other positive things. It is not dangerous to apply to the labia. I am going to call the office and ask that another physician explain the results to me. Compounding HRT is the way to go. The pharmacist can closely duplicate the hormones naturally produced in your body when menopause causes them to produce less.