Saw palmetto reduce testosterone

The fact is it’s important for men to look after their health, particularly as they approach their middle and later years. Time and money invested now, will pay huge dividends later. So, take action and investigate high quality supplements that, down the line, may help prevent prostate problems.

Medical references: 40,41,42,43,44,45,46,47,48,49

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SBI!

I have been taking Saw Palmetto 450 MGS twice a day. I am 67. It is by the Sundown Corp.
For a year, I have taken this product. I think it is worthless. I had to result in going to a Urologist for the many peeing trips in a 24 hour period. I take Tamsulosin twice a day to help urine flow, and oxybutynin er 10 MG once a day, For urine urgency to pee. The OXYBUTNIN is helping. The Tamsulosin is SO SO. I have been having this problem for 4 years. Taking all those advertised prostate products is dangerous and most are worthless. See a Urologist if it is becoming a bathroom problem.

Studies of a hexanic extract of S. repens suggests it decreases prostaglandin and leukotriene production to inhibit the arachidonic acid cascade and decreases B lymphocyte infiltrates and interleukin (IL)-1b and tumor necrosis factor (TNF)-a levels to adjust inflammatory status and gene expression  (36) . In animal models of prostate hyperplasia, it demonstrated a global anti-inflammatory effect on hyperplastic prostates with lobe-specific anti-androgenic effects  (44) . In human prostate and vascular cells in an inflammatory environment, it also decreases monocyte chemotactic protein-1 production and vascular cell adhesion molecule-1 expression  (37) . In human prostate carcinoma cells, inhibitory effects on cell growth were attributed to downregulation of inflammatory-related genes and activation of nuclear factor-kappa B pathway  (45) .

Another study hypothesized that targeting 5AR as well as inflammatory pathways may have positive effects in AGA and benign prostatic hyperplasia, both being treated with 5-alpha reductase inhibitors such as finasteride. After testing hair follicle dermal papilla cells and prostate cells in vitro by exposing them to stigmasterol and beta sitosterol the authors concluded that the naturally derived 5-alpha reductase inhibitors represent a good approach in the treatment of androgenetic alopecia and benign prostatic hyperplasia. (Chen et al.,2016)

Saw palmetto reduce testosterone

saw palmetto reduce testosterone

Another study hypothesized that targeting 5AR as well as inflammatory pathways may have positive effects in AGA and benign prostatic hyperplasia, both being treated with 5-alpha reductase inhibitors such as finasteride. After testing hair follicle dermal papilla cells and prostate cells in vitro by exposing them to stigmasterol and beta sitosterol the authors concluded that the naturally derived 5-alpha reductase inhibitors represent a good approach in the treatment of androgenetic alopecia and benign prostatic hyperplasia. (Chen et al.,2016)

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