Levels of prostate-specific antigen (PSA) should be checked at 3, 6, and 12 months. If the patient is truly hypogonadal to begin with, expect a significant rise at the 3-month assessment. Thereafter, the usual criteria apply regarding the possible presence of an underlying malignancy (>4 ng/mL, or rate of increase > ng/mL/2 yr or >2 ng/mL overall). These criteria continue to be revised by our urology colleagues, tending to become more stringent with time. For example, a PSA rise of more than 1 ng/mL/year has been suggested as an early warning guide, and closer surveillance has been recommended, even at rates of to ng/mL/year. 2 A digital rectal examination should be performed at 3 to 6 months and at 1 year after therapy is initiated. A urologic consultation should be obtained if indicated.
Other side effects include increased risk of heart problems in older men with poor mobility, according to a 2009 study at Boston Medical Center. A 2017 study published in JAMA found that treatments increase coronary artery plaque volume. Additionally, the Food and Drug Administration (FDA) requires manufactures to include a notice on the labeling that states taking testosterone treatments can lead to possible increased risk of heart attacks and strokes. The FDA recommends that patients using testosterone should seek medical attention right away if they have these symptoms:
My brother has been compounding my hormones since 2000. I just saw a doctor who ordered blood tests to check my hormone levels, primarily because my hair won't stop falling out. The doctor's office faxed the results to my brother and she had prescribed testosterone cream on the labia. I didn't like that answer and now the doctor is in Australia until mid January. The way my brother explained it is that the testosterone will increase the libido, it will build up muscle tissue and do several other positive things. It is not dangerous to apply to the labia. I am going to call the office and ask that another physician explain the results to me. Compounding HRT is the way to go. The pharmacist can closely duplicate the hormones naturally produced in your body when menopause causes them to produce less.