Answer: Although I am not a Doctor, in speaking with hundreds of clinicians and immersing myself in all of the latest research, I DO NOT BELIEVE it is common for a long term user to stop responding to HCG therapy. I have not found any human studies in men to demonstrate this either. Anecdotally, I have heard from men who claim that hCG loses its effectiveness when dosed for long periods. Oftentimes men start feeling like it increases E2 production and its resulting side effects. As a proper course of action when using hCG for the long term, I recommend using it only intermittently. Example would be to dose 3 days in a row every 3-4 weeks to maintain testicular size, increase dopamine response and somewhat maintain motile sperm.
If the high cost of medication wasn’t bad enough, blood work and doctor’s visits is where it really starts to pain the wallet. Most offices offer some type of cash discount and in my case it was $65 per visit. You’ll need to obtain at least one blood test for low Testosterone which can set you back roughly $ per test. At some point you’ll need to test your estrogen levels which generally runs $280 + per test. Keep in mind most doctors will want these tests done bi-weekly/monthly when you first start and every 6 months after your T levels have stabilized. (I can’t help but laugh at this statement actually, I’m not sure it ever fully stabilizes)
It’s heart wrenching to hear stories like yours. To lend some insight, I have most of my patients on estrogen blockers as well. This is something that I find necessary even though we replace to the normal range only. We recommend against GHRP-6 and all growth hormone treatment, so I cant’ speak directly to that. His testosterone dose is higher than what I would start a patient at, but it’s not exorbitant. That, however, is only part of the picture. Proper dosing is dependent upon the observation of how a patient reacts to a dose over time. So, that dose could be entirely too high for him even though I would say it is on the spectrum of normal dosing in general.